InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PIP5K1C

Summary

InnateDB Protein

IDBP-764988.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIP5K1C

Protein Name

Synonyms

LCCS3; PIP5K-GAMMA; PIP5K1-gamma; PIP5Kgamma;

Species

Homo sapiens

Ensembl Protein

ENSP00000466363

InnateDB Gene

IDBG-17648 (PIP5K1C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016307	phosphatidylinositol phosphate kinase activity
GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:1990147	talin binding

Biological Process

GO:0006644	phospholipid metabolic process
GO:0006661	phosphatidylinositol biosynthetic process
GO:0006909	phagocytosis
GO:0007016	cytoskeletal anchoring at plasma membrane
GO:0007409	axonogenesis
GO:0007411	axon guidance
GO:0016079	synaptic vesicle exocytosis
GO:0016337	single organismal cell-cell adhesion
GO:0030036	actin cytoskeleton organization
GO:0030593	neutrophil chemotaxis
GO:0034333	adherens junction assembly
GO:0044281	small molecule metabolic process
GO:0046488	phosphatidylinositol metabolic process
GO:0046854	phosphatidylinositol phosphorylation
GO:0048488	synaptic vesicle endocytosis
GO:0070527	platelet aggregation
GO:0072583	clathrin-mediated endocytosis

Cellular Component

GO:0001891	phagocytic cup
GO:0001931	uropod
GO:0005634	nucleus
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0012505	endomembrane system
GO:0032587	ruffle membrane