Homo sapiens Protein: ARHGEF1
Summary
InnateDB Protein IDBP-765216.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF1
Protein Name
Synonyms GEF1; LBCL2; LSC; P115-RHOGEF; SUB1.5;
Species Homo sapiens
Ensembl Protein ENSP00000473229
InnateDB Gene IDBG-53394 (ARHGEF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0038032 termination of G-protein coupled receptor signaling pathway
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR015212 Regulator of G protein signalling-like domain
IPR016137 Regulator of G protein signalling superfamily
PFAM PF09128
PRINTS
PIRSF
SMART SM00315
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 9138
UniGene Hs.729222
RefSeq
HUGO HGNC:681
OMIM 601855
CCDS
HPRD 03511
IMGT
EMBL
GenPept