InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPS4X

Summary

InnateDB Protein

IDBP-76539.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS4X

Protein Name

ribosomal protein S4, X-linked

Synonyms

CCG2; DXS306; RPS4; S4; SCAR; SCR10;

Species

Homo sapiens

Ensembl Protein

ENSP00000362744

InnateDB Gene

IDBG-76537 (RPS4X)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 194 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	194 [view]
Protein-Protein	194 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0007275	multicellular organismal development
GO:0008284	positive regulation of cell proliferation
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process
GO:0045727	positive regulation of translation

Cellular Component

GO:0005622	intracellular
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005844	polysome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022627	cytosolic small ribosomal subunit
GO:0030529	ribonucleoprotein complex
GO:0036464	cytoplasmic ribonucleoprotein granule
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000876 Ribosomal protein S4e
IPR002942 RNA-binding S4 domain
IPR005824 KOW
IPR013843 Ribosomal protein S4e, N-terminal
IPR013845 Ribosomal protein S4e, central region

PFAM

PF01479
PF00467
PF08071
PF00900

PRINTS

PIRSF

PIRSF002116

SMART

SM00363
SM00739

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt