InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IL11

Summary

InnateDB Protein

IDBP-765436.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IL11

Protein Name

Synonyms

AGIF; IL-11;

Species

Homo sapiens

Ensembl Protein

ENSP00000465705

InnateDB Gene

IDBG-70602 (IL11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	6 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005142	interleukin-11 receptor binding
GO:0008083	growth factor activity

Biological Process

GO:0007267	cell-cell signaling
GO:0008284	positive regulation of cell proliferation
GO:0030183	B cell differentiation
GO:0030219	megakaryocyte differentiation
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0043410	positive regulation of MAPK cascade
GO:0045444	fat cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046888	negative regulation of hormone secretion
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation