Version 5.4
Homo sapiens Protein: MBD3
Summary
InnateDB Protein IDBP-766028.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MBD3
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000466670
InnateDB Gene IDBG-14805 (MBD3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 95 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 95 [view]
Protein-Protein 90 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008327 methyl-CpG binding
GO:0031492 nucleosomal DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0043044 ATP-dependent chromatin remodeling
Cellular Component
GO:0000790 nuclear chromatin
GO:0016581 NuRD complex
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR016177 DNA-binding domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95983
PhosphoSite PhosphoSite-O95983
TrEMBL
UniProt Splice Variant
Entrez Gene 53615
UniGene Hs.178728
RefSeq
HUGO HGNC:6918
OMIM 603573
CCDS
HPRD 04653
IMGT
EMBL AC005943 AF072247 AK290882 BC009372 BC009438 BC032443 BC043619 CH471139
GenPept AAC68876 AAC72104 AAH09372 AAH09438 AAH32443 AAH43619 BAF83571 EAW69477 EAW69478 EAW69481

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca