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InnateDB Protein
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IDBP-766124.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ARHGEF1
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Protein Name
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Synonyms
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GEF1; LBCL2; LSC; P115-RHOGEF; SUB1.5;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000470557
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InnateDB Gene
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IDBG-53394 (ARHGEF1)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
33
[view]
|
| Protein-Protein |
33
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
8 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0005089
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Rho guanyl-nucleotide exchange factor activity
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| Biological Process |
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GO:0032321
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positive regulation of Rho GTPase activity
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GO:0035023
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regulation of Rho protein signal transduction
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR000219
Dbl homology (DH) domain
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| PFAM |
PF00621
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| PRINTS |
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| PIRSF |
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| SMART |
SM00325
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
M0QZH8
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| UniProt Splice Variant |
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| Entrez Gene |
9138
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| UniGene |
Hs.729222
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| RefSeq |
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| HUGO |
HGNC:681
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| OMIM |
601855
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| CCDS |
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| HPRD |
03511
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| IMGT |
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| EMBL |
AC010616
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| GenPept |
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Version 5.4