Version 5.4
Homo sapiens Protein: INPP1
Summary
InnateDB Protein IDBP-77527.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INPP1
Protein Name inositol polyphosphate-1-phosphatase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000325423
InnateDB Gene IDBG-77525 (INPP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitously expressed, with highest levels in pancreas and kidney.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
GO:0052829 inositol-1,3,4-trisphosphate 1-phosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
GO:0007165 signal transduction
GO:0016311 dephosphorylation
GO:0043647 inositol phosphate metabolic process
GO:0044281 small molecule metabolic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000760 Inositol monophosphatase
PFAM PF00459
PRINTS PR00377
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49441
PhosphoSite PhosphoSite-P49441
TrEMBL Q6IBG4
UniProt Splice Variant
Entrez Gene 3628
UniGene Hs.32309
RefSeq NP_002185
HUGO HGNC:6071
OMIM 147263
CCDS CCDS2305
HPRD 00923
IMGT
EMBL AC092178 AF141325 BC015496 BC106006 CH471058 CR456840 CR541707 L08488
GenPept AAA36117 AAD46766 AAH15496 AAI06007 AAY24179 CAG33121 CAG46508 EAX10869 EAX10871 EAX10872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca