InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sstr2

Summary

InnateDB Protein

IDBP-789518.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sstr2

Protein Name

somatostatin receptor 2

Synonyms

Smstr-2; Smstr2; sst2; SSTR-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138101

InnateDB Gene

IDBG-214022 (Sstr2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004994	somatostatin receptor activity
GO:0005515	protein binding
GO:0030165	PDZ domain binding

Biological Process

GO:0006937	regulation of muscle contraction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0007283	spermatogenesis
GO:0021549	cerebellum development
GO:0030432	peristalsis
GO:0030900	forebrain development
GO:0038170	somatostatin signaling pathway
GO:0042594	response to starvation
GO:0071385	cellular response to glucocorticoid stimulus
GO:0071392	cellular response to estradiol stimulus

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:98328

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000586 Somatostatin receptor family
IPR000611 Neuropeptide Y receptor family
IPR001184 Somatostatin receptor 5
IPR001418 Opioid receptor
IPR002074 Somatostatin receptor 2
IPR009150 Neuropeptide B/W receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019426 7TM GPCR, serpentine receptor class v (Srv)
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10323
PF10328

PRINTS