Mus musculus Protein: Birc2
Summary
InnateDB Protein IDBP-789532.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Birc2
Protein Name baculoviral IAP repeat-containing 2
Synonyms Api1; Api2; AW146227; Birc3; cIAP1; cIAP2; HIAP1; HIAP2; IAP1; IAP2; mcIAP1; MIAP1; MIAP2; MIHB; MIHC; RNF48;
Species Mus musculus
Ensembl Protein ENSMUSP00000140049
InnateDB Gene IDBG-133125 (Birc2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 105 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 105 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0047485 protein N-terminus binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0001666 response to hypoxia
GO:0001890 placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0010243 response to organonitrogen compound
GO:0014070 response to organic cyclic compound
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045471 response to ethanol
GO:0051291 protein heterooligomerization
GO:0051591 response to cAMP
GO:0051726 regulation of cell cycle
GO:0060544 regulation of necroptotic process
GO:0060546 negative regulation of necroptotic process
GO:0070266 necroptotic process
GO:1902443 negative regulation of ripoptosome assembly involved in necroptotic process
GO:1902523 positive regulation of protein K63-linked ubiquitination
GO:1902524 positive regulation of protein K48-linked ubiquitination
GO:1902527 positive regulation of protein monoubiquitination
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
GO:0001741 XY body
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0009898 cytoplasmic side of plasma membrane
GO:0035631 CD40 receptor complex
GO:0043234 protein complex
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID MGI:1197009
InterPro IPR001315 CARD domain
IPR001370 Baculoviral inhibition of apoptosis protein repeat
IPR001841 Zinc finger, RING-type
IPR011029 Death-like domain
PFAM PF00619
PF00653
PF13639
PF14634
PRINTS
PIRSF
SMART SM00114
SM00238
SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 11797
UniGene
RefSeq XP_006509896
MGI ID
MGI Symbol Birc2
OMIM
CCDS CCDS22811
HPRD
IMGT
EMBL BC145985 L49433 U88909
GenPept AAC42078 AAC53532 AAI45986