InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pecam1

Summary

InnateDB Protein

IDBP-789931.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pecam1

Protein Name

platelet/endothelial cell adhesion molecule 1

Synonyms

C85791; Cd31; Pecam; PECAM-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138959

InnateDB Gene

IDBG-213505 (Pecam1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0002687	positive regulation of leukocyte migration
GO:0006928	cellular component movement
GO:0007155	cell adhesion
GO:0007266	Rho protein signal transduction
GO:0030334	regulation of cell migration
GO:0030837	negative regulation of actin filament polymerization
GO:0034097	response to cytokine
GO:0034259	negative regulation of Rho GTPase activity
GO:0042060	wound healing
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation

Cellular Component

GO:0005886	plasma membrane
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030485	smooth muscle contractile fiber
GO:0045121	membrane raft
GO:0071944	cell periphery