InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EPHX1

Summary

InnateDB Protein

IDBP-806649.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EPHX1

Protein Name

epoxide hydrolase 1, microsomal (xenobiotic)

Synonyms

EPHX; EPOX; HYL1; MEH;

Species

Homo sapiens

Ensembl Protein

ENSP00000480004

InnateDB Gene

IDBG-106969 (EPHX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	7 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004301	epoxide hydrolase activity
GO:0033961	cis-stilbene-oxide hydrolase activity

Biological Process

GO:0006725	cellular aromatic compound metabolic process
GO:0009636	response to toxic substance
GO:0014070	response to organic cyclic compound
GO:0019439	aromatic compound catabolic process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000073 Alpha/beta hydrolase fold-1
IPR000639 Epoxide hydrolase-like
IPR010497 Epoxide hydrolase, N-terminal
IPR016292 Epoxide hydrolase
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00561
PF06441

PRINTS

PR00111
PR00412

PIRSF

PIRSF001112

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt