InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HLA-DRA

Summary

InnateDB Protein

IDBP-80800.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HLA-DRA

Protein Name

major histocompatibility complex, class II, DR alpha

Synonyms

HLA-DRA1; MLRW;

Species

Homo sapiens

Ensembl Protein

ENSP00000364121

InnateDB Gene

IDBG-80796 (HLA-DRA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.

Experimentally validated
Total	29 [view]
Protein-Protein	26 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955	immune response
GO:0019882	antigen processing and presentation

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042613	MHC class II protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001003 MHC class II, alpha chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR011162 MHC classes I/II-like antigen recognition protein

PFAM

PF00993
PF07654

PRINTS

PIRSF

SMART

SM00920
SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q30118

UniProt Splice Variant

Entrez Gene

3122

UniGene

RefSeq

HUGO

HGNC:4947

OMIM

142860

CCDS

HPRD

00833

IMGT

EMBL

AL662796 AY669056 M35979 M60333 V00524 V00528

GenPept

AAA36283 AAA59787 AAV74560 CAA23783 CAA23787