InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HLA-E

Summary

InnateDB Protein

IDBP-808177.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HLA-E

Protein Name

major histocompatibility complex, class I, E

Synonyms

EA1.2; EA2.1; HLA-6.2; MHC; QA1;

Species

Homo sapiens

Ensembl Protein

ENSP00000480643

InnateDB Gene

IDBG-125081 (HLA-E)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006955	immune response
GO:0019882	antigen processing and presentation

Cellular Component

GO:0016020	membrane
GO:0042612	MHC class I protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR010579 MHC class I, alpha chain, C-terminal
IPR011162 MHC classes I/II-like antigen recognition protein
IPR013162 CD80-like, immunoglobulin C2-set
IPR027648 MHC class I alpha chain

PFAM

PF00129
PF07654
PF06623
PF08205

PRINTS

PR01638

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt