Version 5.4
Homo sapiens Protein: POLR2E
Summary
InnateDB Protein IDBP-808485.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLR2E
Protein Name polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
Synonyms hRPB25; hsRPB5; RPABC1; RPB5; XAP4;
Species Homo sapiens
Ensembl Protein ENSP00000480562
InnateDB Gene IDBG-13793 (POLR2E)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 109 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 109 [view]
Protein-Protein 106 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal
IPR005571 RNA polymerase, Rpb5, N-terminal
PFAM PF01191
PF03871
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DJ89
UniProt Splice Variant
Entrez Gene 5434
UniGene
RefSeq
HUGO HGNC:9192
OMIM 180664
CCDS
HPRD
IMGT
EMBL AK295975 CH471139
GenPept BAG58751 EAW69550

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca