InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: VEGFC

Summary

InnateDB Protein

IDBP-808734.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

VEGFC

Protein Name

vascular endothelial growth factor C

Synonyms

Flt4-L; LMPH1D; VRP;

Species

Homo sapiens

Ensembl Protein

ENSP00000480043

InnateDB Gene

IDBG-45463 (VEGFC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	4 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0042056	chemoattractant activity
GO:0043185	vascular endothelial growth factor receptor 3 binding

Biological Process

GO:0001525	angiogenesis
GO:0001954	positive regulation of cell-matrix adhesion
GO:0002052	positive regulation of neuroblast proliferation
GO:0002576	platelet degranulation
GO:0006929	substrate-dependent cell migration
GO:0007165	signal transduction
GO:0007596	blood coagulation
GO:0008284	positive regulation of cell proliferation
GO:0008285	negative regulation of cell proliferation
GO:0009887	organ morphogenesis
GO:0016331	morphogenesis of embryonic epithelium
GO:0030168	platelet activation
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031954	positive regulation of protein autophosphorylation
GO:0042493	response to drug
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0045766	positive regulation of angiogenesis
GO:0045776	negative regulation of blood pressure
GO:0048010	vascular endothelial growth factor receptor signaling pathway
GO:0050679	positive regulation of epithelial cell proliferation
GO:0050714	positive regulation of protein secretion
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918	positive chemotaxis
GO:0050930	induction of positive chemotaxis
GO:0051781	positive regulation of cell division
GO:0060754	positive regulation of mast cell chemotaxis
GO:1901492	positive regulation of lymphangiogenesis