InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDX1

Summary

InnateDB Protein

IDBP-809046.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX1

Protein Name

DEAD (Asp-Glu-Ala-Asp) box helicase 1

Synonyms

DBP-RB; UKVH5d;

Species

Homo sapiens

Ensembl Protein

ENSP00000484958

InnateDB Gene

IDBG-30761 (DDX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 130 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	130 [view]
Protein-Protein	128 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00622
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00449
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite