Version 5.4
Homo sapiens Protein: BIRC2
Summary
InnateDB Protein IDBP-809726.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BIRC2
Protein Name baculoviral IAP repeat containing 2
Synonyms API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48;
Species Homo sapiens
Ensembl Protein ENSP00000484838
InnateDB Gene IDBG-69075 (BIRC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 184 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 184 [view]
Protein-Protein 179 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042981 regulation of apoptotic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001315 CARD domain
IPR001370 Baculoviral inhibition of apoptosis protein repeat
IPR011029 Death-like domain
PFAM PF00619
PF00653
PRINTS
PIRSF
SMART SM00114
SM00238
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PNM6
UniProt Splice Variant
Entrez Gene 329
UniGene
RefSeq
HUGO HGNC:590
OMIM 601712
CCDS
HPRD
IMGT
EMBL AP000942
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca