Version 5.4
Homo sapiens Protein: SLC11A1
Summary
InnateDB Protein IDBP-80973.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC11A1
Protein Name solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Synonyms LSH; NRAMP; NRAMP1;
Species Homo sapiens
Ensembl Protein ENSP00000346320
InnateDB Gene IDBG-80969 (SLC11A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 0
Protein-DNA 6 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
GO:0006955 immune response
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001046 NRAMP family
PFAM PF01566
PRINTS PR00447
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9HBK0
UniProt Splice Variant
Entrez Gene 6556
UniGene Hs.627035
RefSeq
HUGO HGNC:10907
OMIM 600266
CCDS
HPRD 02601
IMGT
EMBL AC021016 AF229163 AJ494846 AK294707 L38592 L38593
GenPept AAA57556 AAG15403 BAG57862 CAD39201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca