InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SETDB2

Summary

InnateDB Protein

IDBP-810055.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SETDB2

Protein Name

SET domain, bifurcated 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000482240

InnateDB Gene

IDBG-33315 (SETDB2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0018024	histone-lysine N-methyltransferase activity

Biological Process

GO:0034968

histone lysine methylation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001214 SET domain
IPR001739 Methyl-CpG DNA binding
IPR003606 Pre-SET zinc-binding sub-group
IPR007728 Pre-SET domain
IPR016177 DNA-binding domain

PFAM

PF00856
PF01429
PF05033

PRINTS

PIRSF

SMART

SM00317
SM00391
SM00468

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8NDJ9

UniProt Splice Variant

Entrez Gene

83852

UniGene

RefSeq

XP_005266629

HUGO

HGNC:20263

OMIM

607865

CCDS

HPRD

IMGT

EMBL

AL833957

GenPept

CAD38807