Version 5.4
Homo sapiens Protein: DMBT1
Summary
InnateDB Protein IDBP-810130.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DMBT1
Protein Name deleted in malignant brain tumors 1
Synonyms GP340; muclin;
Species Homo sapiens
Ensembl Protein ENSP00000484603
InnateDB Gene IDBG-91946 (DMBT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0008329 signaling pattern recognition receptor activity
GO:0035375 zymogen binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0002221 pattern recognition receptor signaling pathway
GO:0006898 receptor-mediated endocytosis
GO:0015031 protein transport
GO:0016032 viral process
GO:0030855 epithelial cell differentiation
GO:0043152 induction of bacterial agglutination
GO:0045087 innate immune response (InnateDB)
GO:0051607 defense response to virus
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0019898 extrinsic component of membrane
GO:0030670 phagocytic vesicle membrane
GO:0042589 zymogen granule membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000859 CUB domain
IPR001190 SRCR domain
IPR001507 Zona pellucida domain
IPR017448 SRCR-like domain
PFAM PF00431
PF00530
PF00100
PRINTS PR00258
PR00023
PIRSF
SMART SM00042
SM00241
SM00202
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B6V682
UniProt Splice Variant
Entrez Gene 1755
UniGene
RefSeq XP_006717731
HUGO HGNC:2926
OMIM 601969
CCDS
HPRD
IMGT
EMBL AB020851 AB209691 AF159456 AJ000342 AJ243211 AJ243212 AJ243224 AJ297935 AK304149 AL603764 BC153299 BX640988 FJ234410
GenPept AAD49696 AAI53300 ACI95281 BAA78577 BAD92928 BAH14118 CAA04019 CAB56155 CAB63941 CAB63942 CAC44122 CAE45995 CAI14487 CAI14488 CAI14489 CAI14490 CAI14491 CAI14492 CAI14493 CAI14494 CAI14495 CAI14496

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca