InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ENC1

Summary

InnateDB Protein

IDBP-810134.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ENC1

Protein Name

ectodermal-neural cortex 1 (with BTB domain)

Synonyms

CCL28; ENC-1; KLHL35; KLHL37; NRPB; PIG10; TP53I10;

Species

Homo sapiens

Ensembl Protein

ENSP00000479101

InnateDB Gene

IDBG-28385 (ENC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.

Experimentally validated
Total	18 [view]
Protein-Protein	17 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0007275	multicellular organismal development
GO:0007399	nervous system development
GO:0010499	proteasomal ubiquitin-independent protein catabolic process
GO:0010976	positive regulation of neuron projection development
GO:0016567	protein ubiquitination
GO:0017148	negative regulation of translation

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0016363	nuclear matrix
GO:0031463	Cul3-RING ubiquitin ligase complex
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011498 Kelch repeat type 2
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
IPR017096 Kelch-like protein, gigaxonin type

PFAM

PF01344
PF07646
PF07707
PF00651

PRINTS

PIRSF

PIRSF037037

SMART

SM00225
SM00612
SM00875

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt