InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PCGF2

Summary

InnateDB Protein

IDBP-810233.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCGF2

Protein Name

polycomb group ring finger 2

Synonyms

MEL-18; RNF110; ZNF144;

Species

Homo sapiens

Ensembl Protein

ENSP00000482815

InnateDB Gene

IDBG-775251 (PCGF2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 68 experimentally validated interaction(s) in this database.

Experimentally validated
Total	68 [view]
Protein-Protein	66 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0031519	PcG protein complex
GO:0035102	PRC1 complex

Protein Structure and Domains

PDB ID

InterPro

IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF13639
PF14634
PF00097

PRINTS

PIRSF

SMART

SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P35227

PhosphoSite

PhosphoSite-P35227

TrEMBL

A0A024R1V6

UniProt Splice Variant

Entrez Gene

7703

UniGene

RefSeq

NP_009075

HUGO

HGNC:12929

OMIM

600346

CCDS

CCDS32638

HPRD

IMGT

EMBL

AC006449 BC004858 BC024255 BX647429 CH471152 D13969

GenPept

AAH04858 AAH24255 BAA03074 EAW60528 EAW60529