InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNAJC3

Summary

InnateDB Protein

IDBP-810353.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNAJC3

Protein Name

DnaJ (Hsp40) homolog, subfamily C, member 3

Synonyms

ERdj6; HP58; P58; P58IPK; PRKRI;

Species

Homo sapiens

Ensembl Protein

ENSP00000473631

InnateDB Gene

IDBG-43059 (DNAJC3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004860	protein kinase inhibitor activity
GO:0005515	protein binding
GO:0051087	chaperone binding
GO:0051787	misfolded protein binding

Biological Process

GO:0006469	negative regulation of protein kinase activity
GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0044267	cellular protein metabolic process
GO:0051603	proteolysis involved in cellular protein catabolic process
GO:0051607	defense response to virus

Cellular Component

GO:0005737	cytoplasm
GO:0005788	endoplasmic reticulum lumen
GO:0005790	smooth endoplasmic reticulum
GO:0016020	membrane
GO:0031205	endoplasmic reticulum Sec complex
GO:0070062	extracellular vesicular exosome