Version 5.4
Homo sapiens Protein: KCNN3
Summary
InnateDB Protein IDBP-810434.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNN3
Protein Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
Synonyms hSK3; KCa2.3; SK3; SKCA3;
Species Homo sapiens
Ensembl Protein ENSP00000481848
InnateDB Gene IDBG-102975 (KCNN3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005516 calmodulin binding
GO:0015269 calcium-activated potassium channel activity
GO:0016286 small conductance calcium-activated potassium channel activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030175 filopodium
GO:0031594 neuromuscular junction
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0044297 cell body
Protein Structure and Domains
PDB ID
InterPro IPR004178 Calmodulin-binding domain
IPR013099 Two pore domain potassium channel domain
IPR015449 Potassium channel, calcium-activated, SK
PFAM PF02888
PF07885
PF03530
PRINTS PR01451
PIRSF
SMART SM01053
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 3782
UniGene
RefSeq NP_001191016
HUGO HGNC:6292
OMIM 602983
CCDS CCDS72928
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca