InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CHD1

Summary

InnateDB Protein

IDBP-810679.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHD1

Protein Name

chromodomain helicase DNA binding protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000483667

InnateDB Gene

IDBG-35192 (CHD1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	58 [view]
Protein-Protein	57 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004003	ATP-dependent DNA helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0035064	methylated histone binding

Biological Process

GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0032508	DNA duplex unwinding

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000330 SNF2-related
IPR000953 Chromo domain/shadow
IPR001650 Helicase, C-terminal
IPR009057 Homeodomain-like
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR016197 Chromo domain-like
IPR023780 Chromo domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF00385

PRINTS

PIRSF

SMART

SM00298
SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite