Version 5.4
Homo sapiens Protein: DSTN
Summary
InnateDB Protein IDBP-811106.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DSTN
Protein Name destrin (actin depolymerizing factor)
Synonyms ACTDP; ADF; bA462D18.2; HEL32;
Species Homo sapiens
Ensembl Protein ENSP00000476975
InnateDB Gene IDBG-56056 (DSTN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
Experimentally validated
Total 69 [view]
Protein-Protein 69 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0008154 actin polymerization or depolymerization
GO:0030042 actin filament depolymerization
GO:0051014 actin filament severing
Cellular Component
GO:0005622 intracellular
GO:0015629 actin cytoskeleton
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002108 Actin-depolymerising factor homology domain
IPR017904 ADF/Cofilin/Destrin
PFAM PF00241
PRINTS PR00006
PIRSF
SMART SM00102
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60981
PhosphoSite PhosphoSite-P60981
TrEMBL
UniProt Splice Variant
Entrez Gene 11034
UniGene
RefSeq NP_001011546
HUGO HGNC:15750
OMIM 609114
CCDS CCDS46580
HPRD
IMGT
EMBL AK302338 AK312645 AL132765 BC009477 CH471133 CR457042 S65738
GenPept AAB28361 AAH09477 BAG35529 BAG63668 CAC10585 CAG33323 EAX10274 EAX10275 EAX10276

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca