Version 5.4
Homo sapiens Protein: NT5C3
Summary
InnateDB Protein IDBP-811474.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NT5C3
Protein Name 5'-nucleotidase, cytosolic IIIA
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000484415
InnateDB Gene IDBG-11769 (NT5C3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0008253 5'-nucleotidase activity
GO:0008665 2'-phosphotransferase activity
Biological Process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0006213 pyrimidine nucleoside metabolic process
GO:0009117 nucleotide metabolic process
GO:0016311 dephosphorylation
GO:0044281 small molecule metabolic process
GO:0046085 adenosine metabolic process
GO:0046135 pyrimidine nucleoside catabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR006434 Pyrimidine 5\'-nucleotidase, eukaryotic
IPR023214 HAD-like domain
PFAM PF05822
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL X6RM59
UniProt Splice Variant
Entrez Gene 51251
UniGene
RefSeq NP_001002010
HUGO HGNC:17820
OMIM 606224
CCDS CCDS34616
HPRD
IMGT
EMBL AC074338 AC083863 AF151067 AF312735 AK290118 AK314109 AL136716 BC013292 BC015856 BC066914 BC071652 CH471073 CR533518
GenPept AAF36153 AAG33630 AAH13292 AAH15856 AAH66914 AAH71652 BAF82807 BAG36802 CAB66650 CAG38549 EAW94007 EAW94008

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca