InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HHLA2

Summary

InnateDB Protein

IDBP-811732.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HHLA2

Protein Name

HERV-H LTR-associating 2

Synonyms

B7H7;

Species

Homo sapiens

Ensembl Protein

ENSP00000482187

InnateDB Gene

IDBG-48892 (HHLA2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0001819	positive regulation of cytokine production
GO:0031295	T cell costimulation
GO:0042104	positive regulation of activated T cell proliferation

Cellular Component

GO:0005575	cellular_component
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003597 Immunoglobulin C1-set
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain

PFAM

PF07654
PF07686

PRINTS

PIRSF

SMART

SM00406
SM00407
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

C9JY43

UniProt Splice Variant

Entrez Gene

11148

UniGene

RefSeq

NP_001269485

HUGO

HGNC:4905

OMIM

604371

CCDS

CCDS46883

HPRD

IMGT

EMBL

AC078855 AC135308 AF126162 AK000692 AK296644 BC035971 CH471052

GenPept

AAD48396 AAH35971 BAA91323 BAG59244 EAW79727 EAW79728