Homo sapiens Protein: SEPT2
Summary
InnateDB Protein IDBP-812158.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT2
Protein Name septin 2
Synonyms DIFF6; hNedd5; NEDD-5; NEDD5; Pnutl3;
Species Homo sapiens
Ensembl Protein ENSP00000479861
InnateDB Gene IDBG-85139 (SEPT2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 71 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 71 [view]
Protein-Protein 71 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0030234 enzyme regulator activity
GO:0032947 protein complex scaffold
Biological Process
GO:0002036 regulation of L-glutamate transport
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0007224 smoothened signaling pathway
GO:0031175 neuron projection development
GO:0032880 regulation of protein localization
GO:0042384 cilium assembly
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0000145 exocyst
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0009986 cell surface
GO:0015629 actin cytoskeleton
GO:0030496 midbody
GO:0031105 septin complex
GO:0032154 cleavage furrow
GO:0035869 ciliary transition zone
GO:0042995 cell projection
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0060170 ciliary membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000038 Cell division protein GTP binding
IPR008113 Septin 2
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00735
PRINTS PR01740
PIRSF PIRSF006698
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JZI2
UniProt Splice Variant
Entrez Gene 4735
UniGene
RefSeq NP_001269901
HUGO HGNC:7729
OMIM 601506
CCDS CCDS74682
HPRD
IMGT
EMBL AC005104 AC104841 AF038404 AK294563 BC014455 BC033559 D28540 D63878
GenPept AAB92377 AAH14455 AAH33559 AAY14718 BAA05893 BAA09928 BAG57759