Version 5.4
Homo sapiens Gene: SEPT2
Summary
InnateDB Gene IDBG-85139.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT2
Gene Name septin 2
Synonyms DIFF6; hNedd5; NEDD-5; NEDD5; Pnutl3
Species Homo sapiens
Ensembl Gene ENSG00000168385
Encoded Proteins
IDBP-85141
septin 2
IDBP-246607
septin 2
IDBP-246611
septin 2
IDBP-295039
septin 2
IDBP-295597
septin 2
IDBP-292380
septin 2
IDBP-292381
septin 2
IDBP-389673
septin 2
IDBP-389674
septin 2
IDBP-389675
septin 2
IDBP-389676
septin 2
IDBP-389677
septin 2
IDBP-389678
septin 2
IDBP-389679
septin 2
IDBP-389680
septin 2
IDBP-389681
septin 2
IDBP-389682
septin 2
IDBP-389683
septin 2
IDBP-389684
septin 2
IDBP-389685
septin 2
IDBP-389686
septin 2
IDBP-389688
septin 2
IDBP-389689
septin 2
IDBP-389690
septin 2
IDBP-812158
septin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:241315100-241354027
Strand Forward strand
Band q37.3
Transcripts
ENST00000360051 ENSP00000353157
ENST00000366210
ENST00000391973 ENSP00000375834
ENST00000391971 ENSP00000375832
ENST00000401990 ENSP00000385109
ENST00000402092 ENSP00000385172
ENST00000407971 ENSP00000384525
ENST00000407017 ENSP00000386001
ENST00000428282 ENSP00000397195
ENST00000445030 ENSP00000404484
ENST00000428524 ENSP00000389174
ENST00000457335 ENSP00000397290
ENST00000436795 ENSP00000406181
ENST00000411484 ENSP00000394666
ENST00000434955 ENSP00000399767
ENST00000441533 ENSP00000413031
ENST00000425899 ENSP00000403287
ENST00000443492 ENSP00000399195
ENST00000437066 ENSP00000412434
ENST00000429791 ENSP00000404417
ENST00000420786 ENSP00000409596
ENST00000449239 ENSP00000391717
ENST00000457874 ENSP00000408902
ENST00000421717 ENSP00000408296
ENST00000451310 ENSP00000402256
ENST00000492978
ENST00000469434
ENST00000495463
ENST00000482304
ENST00000475474
ENST00000469175
ENST00000461048
ENST00000494824
ENST00000462147
ENST00000466211
ENST00000484740
ENST00000473479
ENST00000464128
ENST00000467971
ENST00000484648
ENST00000475823
ENST00000476841
ENST00000484167
ENST00000481500
ENST00000616972 ENSP00000479861
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 71 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 71 [view]
Protein-Protein 71 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0030234 enzyme regulator activity
GO:0032947 protein complex scaffold
Biological Process
GO:0002036 regulation of L-glutamate transport
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0007224 smoothened signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0031175 neuron projection development
GO:0032880 regulation of protein localization
GO:0042384 cilium assembly
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0000145 exocyst
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0009986 cell surface
GO:0015629 actin cytoskeleton
GO:0030496 midbody
GO:0031105 septin complex
GO:0032154 cleavage furrow
GO:0035869 ciliary transition zone
GO:0042995 cell projection
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0060170 ciliary membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026276
View Gene Order
ENSBTAG00000002608
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
cdc42_pathway
CDC42 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.721234
RefSeq NM_001008491 NM_001008492 NM_001282972 NM_001282973 NM_004404 NM_006155 XM_005247011 XM_005247012 XM_005247013 XM_006712546 XM_006712547 XM_006712548 XM_006712549 XM_006712550
HUGO
OMIM
CCDS CCDS2548 CCDS63195 CCDS74682
HPRD 03297
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca