InnateDB Protein
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IDBP-81216.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CDK5R2
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Protein Name
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cyclin-dependent kinase 5, regulatory subunit 2 (p39)
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Synonyms
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NCK5AI; P39; p39nck5ai;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000304250
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InnateDB Gene
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IDBG-81214 (CDK5R2)
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Protein Structure
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Function |
Activator of CDK5/TPKII.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:18507738}; Lipid-anchor {ECO:0000269PubMed:18507738}; Cytoplasmic side {ECO:0000269PubMed:18507738}.
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Disease Associations |
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Tissue Specificity |
Brain and neuron specific.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008289
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lipid binding
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GO:0016534
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cyclin-dependent protein kinase 5 activator activity
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Biological Process |
GO:0000079
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regulation of cyclin-dependent protein serine/threonine kinase activity
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GO:0001764
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neuron migration
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GO:0021549
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cerebellum development
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GO:0021722
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superior olivary nucleus maturation
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GO:0021766
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hippocampus development
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GO:0021819
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layer formation in cerebral cortex
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GO:0045860
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positive regulation of protein kinase activity
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GO:0045956
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positive regulation of calcium ion-dependent exocytosis
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GO:0071902
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positive regulation of protein serine/threonine kinase activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR004944
Cyclin-dependent kinase 5 activator
IPR013763
Cyclin-like
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PFAM |
PF03261
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PRINTS |
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PIRSF |
PIRSF009324
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SMART |
SM00385
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TIGRFAMs |
|
Modification |
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SwissProt |
Q13319
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PhosphoSite |
PhosphoSite-Q13319
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TrEMBL |
Q96G76
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UniProt Splice Variant |
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Entrez Gene |
8941
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UniGene |
Hs.741488
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RefSeq |
NP_003927
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HUGO |
HGNC:1776
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OMIM |
603764
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CCDS |
CCDS2427
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HPRD |
04790
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IMGT |
|
EMBL |
AC097468
BT007437
DQ307839
U34051
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GenPept |
AAC50278
AAP36105
AAX88916
ABB96255
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