InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CCL4

Summary

InnateDB Protein

IDBP-812241.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CCL4

Protein Name

chemokine (C-C motif) ligand 4

Synonyms

ACT2; AT744.1; G-26; HC21; LAG-1; LAG1; MIP-1-beta; MIP1B; MIP1B1; SCYA2; SCYA4;

Species

Homo sapiens

Ensembl Protein

ENSP00000482259

InnateDB Gene

IDBG-776851 (CCL4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0008009	chemokine activity
GO:0031726	CCR1 chemokine receptor binding
GO:0031730	CCR5 chemokine receptor binding
GO:0042802	identical protein binding

Biological Process

GO:0006928	cellular component movement
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0007155	cell adhesion
GO:0007163	establishment or maintenance of cell polarity
GO:0007165	signal transduction
GO:0007267	cell-cell signaling
GO:0009615	response to virus
GO:0009636	response to toxic substance
GO:0043922	negative regulation by host of viral transcription
GO:0050850	positive regulation of calcium-mediated signaling
GO:0051928	positive regulation of calcium ion transport
GO:0060326	cell chemotaxis
GO:2000503	positive regulation of natural killer cell chemotaxis