InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FOXP1

Summary

InnateDB Protein

IDBP-812470.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FOXP1

Protein Name

forkhead box P1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000484803

InnateDB Gene

IDBG-44357 (FOXP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	14 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0002329	pre-B cell differentiation
GO:0002639	positive regulation of immunoglobulin production
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007507	heart development
GO:0007519	skeletal muscle tissue development
GO:0030324	lung development
GO:0033152	immunoglobulin V(D)J recombination
GO:0045214	sarcomere organization
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048745	smooth muscle tissue development
GO:0050679	positive regulation of epithelial cell proliferation
GO:0055007	cardiac muscle cell differentiation
GO:0060043	regulation of cardiac muscle cell proliferation
GO:0061140	lung secretory cell differentiation
GO:0072358	cardiovascular system development
GO:1901249	regulation of lung goblet cell differentiation
GO:1901250	negative regulation of lung goblet cell differentiation
GO:2000727	positive regulation of cardiac muscle cell differentiation