Version 5.4
Homo sapiens Protein: GTF2I
Summary
InnateDB Protein IDBP-813049.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2I
Protein Name general transcription factor IIi
Synonyms BAP135; BTKAP1; DIWS; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6;
Species Homo sapiens
Ensembl Protein ENSP00000460070
InnateDB Gene IDBG-777373 (GTF2I)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 106 experimentally validated interaction(s) in this database.
Experimentally validated
Total 106 [view]
Protein-Protein 104 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0051019 mitogen-activated protein kinase binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007165 signal transduction
GO:0014886 transition between slow and fast fiber
GO:0016525 negative regulation of angiogenesis
GO:0051481 negative regulation of cytosolic calcium ion concentration
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0042995 cell projection
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR004212 GTF2I-like repeat
IPR016659 Transcription factor II-I
PFAM PF02946
PRINTS
PIRSF PIRSF016441
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL X5DR09
UniProt Splice Variant
Entrez Gene 2969
UniGene
RefSeq NP_127492
HUGO HGNC:4659
OMIM 601679
CCDS CCDS5573
HPRD
IMGT
EMBL AC004883 AC005231 AC083884 AF015553 AF035737 AF038967 AF038968 AF038969 AK294935 AK297238 AK299175 BC004472 BC070484 BT007450 CH471200 KJ534860 KJ534862 U77948 Y14946
GenPept AAB48826 AAB70791 AAC08312 AAC08313 AAC08314 AAC08315 AAH04472 AAH70484 AAL93085 AAP36118 AAS07460 AAS07461 AAS07462 AAS07463 AAS07464 AHW56500 AHW56502 BAG58013 BAG59719 BAG61221 CAA75163 EAW69598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca