InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HLA-DRB1

Summary

InnateDB Protein

IDBP-813244.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HLA-DRB1

Protein Name

major histocompatibility complex, class II, DR beta 1

Synonyms

DRB1; DRw10; HLA-DR1B; HLA-DRB; SS1;

Species

Homo sapiens

Ensembl Protein

ENSP00000480667

InnateDB Gene

IDBG-80863 (HLA-DRB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006955	immune response
GO:0019882	antigen processing and presentation

Cellular Component

GO:0016020	membrane
GO:0042613	MHC class II protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000353 MHC class II, beta chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein

PFAM

PF00969
PF07654

PRINTS

PIRSF

SMART

SM00921
SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite