Version 5.4
Homo sapiens Protein: IBTK
Summary
InnateDB Protein IDBP-813574.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IBTK
Protein Name inhibitor of Bruton agammaglobulinemia tyrosine kinase
Synonyms BTBD26; BTKI;
Species Homo sapiens
Ensembl Protein ENSP00000478891
InnateDB Gene IDBG-93669 (IBTK)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR000408 Regulator of chromosome condensation, RCC1
IPR002110 Ankyrin repeat
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR020683 Ankyrin repeat-containing domain
PFAM PF00415
PF00023
PF13606
PF00651
PF11929
PF12796
PRINTS PR00633
PR01415
PIRSF
SMART SM00225
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PDR5
UniProt Splice Variant
Entrez Gene 25998
UniGene
RefSeq
HUGO HGNC:17853
OMIM 606457
CCDS
HPRD
IMGT
EMBL AL050333
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca