InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TH1L

Summary

InnateDB Protein

IDBP-813719.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TH1L

Protein Name

negative elongation factor complex member C/D

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000473290

InnateDB Gene

IDBG-83212 (TH1L)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	47 [view]
Protein-Protein	47 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006366	transcription from RNA polymerase II promoter
GO:0006368	transcription elongation from RNA polymerase II promoter
GO:0010467	gene expression
GO:0016032	viral process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0050434	positive regulation of viral transcription

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0016020	membrane
GO:0032021	NELF complex

Protein Structure and Domains

PDB ID

InterPro

IPR006942 TH1 protein

PFAM

PF04858

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF161479 AJ238374 AJ238375 AJ238379 AK001316 AK023310 AK023927 AK293410 AL109840 BC014952 CH471077

GenPept

AAF29094 AAH14952 BAA91618 BAB14519 BAB14729 BAG56917 CAB64337 CAB64339 CAB64373 CAC09368 EAW75452 EAW75453 EAW75454

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca