InnateDB Protein
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IDBP-82014.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PANK1
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Protein Name
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pantothenate kinase 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000318526
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InnateDB Gene
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IDBG-82008 (PANK1)
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Protein Structure
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Function |
Plays a role in the physiological regulation of the intracellular CoA concentration. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:14523052}.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle. {ECO:0000269PubMed:14523052}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004567
Type II pantothenate kinase
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PFAM |
PF03630
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TE04
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PhosphoSite |
PhosphoSite-Q8TE04
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
53354
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UniGene |
Hs.376351
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RefSeq |
NP_612189
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HUGO |
HGNC:8598
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OMIM |
606160
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CCDS |
CCDS7405
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HPRD |
07549
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IMGT |
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EMBL |
AF355198
AL157400
AY027661
AY027662
AY027663
BC026296
BK000008
BK000009
CH471066
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GenPept |
AAH26296
AAK20916
AAK20917
AAK20918
AAL86371
CAI16826
CAI16827
DAA00002
DAA00003
EAW50131
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