Version 5.4
Homo sapiens Protein: CYP26A1
Summary
InnateDB Protein IDBP-82647.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP26A1
Protein Name cytochrome P450, family 26, subfamily A, polypeptide 1
Synonyms CP26; CYP26; P450RAI; P450RAI1;
Species Homo sapiens
Ensembl Protein ENSP00000360586
InnateDB Gene IDBG-82645 (CYP26A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001972 retinoic acid binding
GO:0005506 iron ion binding
GO:0008401 retinoic acid 4-hydroxylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019825 oxygen binding
GO:0020037 heme binding
Biological Process
GO:0006766 vitamin metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0034653 retinoic acid catabolic process
GO:0044281 small molecule metabolic process
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR001128 Cytochrome P450
IPR002397 Cytochrome P450, B-class
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV
PFAM PF00067
PRINTS PR00385
PR00359
PR00463
PR00465
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43174
PhosphoSite PhosphoSite-O43174
TrEMBL
UniProt Splice Variant
Entrez Gene 1592
UniGene Hs.150595
RefSeq NP_476498
HUGO HGNC:2603
OMIM 602239
CCDS CCDS7427
HPRD 03759
IMGT
EMBL AF005418 AK027560 AL358613 CH471066
GenPept AAB88881 BAG51346 CAH72803 CAH72804 EAW50078 EAW50079

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca