InnateDB Protein
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IDBP-83468.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PHACTR3
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Protein Name
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phosphatase and actin regulator 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000347866
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InnateDB Gene
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IDBG-83464 (PHACTR3)
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Protein Structure
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Function |
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Subcellular Localization |
Nucleus matrix. Note=Localized to the nuclear matrix-intermediate filament scaffold. Isoform 2 is also found in some cytoplasmic extensions.
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Disease Associations |
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Tissue Specificity |
Abundantly expressed in brain. Also found in several tumors such as lung carcinomas, nervous tumors and HL-60 leukemia cells. Isoform 3 is the major form in U-937, GOTO and HL- 60 leukemia cells.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0043086
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negative regulation of catalytic activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR004018
RPEL repeat
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PFAM |
PF02755
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PRINTS |
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PIRSF |
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SMART |
SM00707
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TIGRFAMs |
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Modification |
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SwissProt |
Q96KR7
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PhosphoSite |
PhosphoSite-Q96KR7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
116154
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UniGene |
Hs.631200
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RefSeq |
NP_001186435
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HUGO |
HGNC:15833
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OMIM |
608725
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CCDS |
CCDS42895
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HPRD |
10571
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IMGT |
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EMBL |
AB098521
AB098522
AJ311122
AJ617581
AK098788
AK314493
AK316047
AL121908
AL357503
BC108303
BC117362
BC117364
CH471077
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GenPept |
AAI08304
AAI17363
AAI17365
BAC82348
BAC82349
BAG37093
BAH14418
CAC67489
CAF04087
CAI22517
CAI22518
CAI23227
CAI23228
CAI23229
CAM28339
EAW75428
EAW75429
EAW75430
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