Version 5.4
Homo sapiens Protein: SCLY
Summary
InnateDB Protein IDBP-84396.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCLY
Protein Name selenocysteine lyase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000254663
InnateDB Gene IDBG-84394 (SCLY)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0009000 selenocysteine lyase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0001887 selenium compound metabolic process
GO:0006520 cellular amino acid metabolic process
GO:0006629 lipid metabolic process
GO:0008152 metabolic process
GO:0032868 response to insulin
GO:1900408 negative regulation of cellular response to oxidative stress
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000192 Aminotransferase class V domain
IPR015424 Pyridoxal phosphate-dependent transferase
IPR016454 Cysteine desulfurase, NifS
PFAM PF00266
PRINTS
PIRSF PIRSF005572
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DDP9
UniProt Splice Variant
Entrez Gene 51540
UniGene Hs.731909
RefSeq NP_057594
HUGO HGNC:18161
OMIM 611056
CCDS CCDS2524
HPRD 15303
IMGT
EMBL AC016757 AC016776 AF175767 AK001377 AK293283 BC000586 BC007891 CH471063
GenPept AAF36816 AAH00586 AAH07891 AAY24221 AAY24333 BAA91659 BAG56810 EAW71135 EAW71139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca