InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BOK

Summary

InnateDB Protein

IDBP-85209.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BOK

Protein Name

BCL2-related ovarian killer

Synonyms

BCL2L9; BOKL;

Species

Homo sapiens

Ensembl Protein

ENSP00000314132

InnateDB Gene

IDBG-85207 (BOK)

Protein Structure

UniProt Annotation

Function

May play a role in apoptosis.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in brain, liver, appendix and lymphoid tissues. {ECO:0000269PubMed:9535847}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity
GO:0046983	protein dimerization activity
GO:0051400	BH domain binding

Biological Process

GO:0006915	apoptotic process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420	brain development
GO:0008283	cell proliferation
GO:0008584	male gonad development
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0042981	regulation of apoptotic process
GO:0043065	positive regulation of apoptotic process
GO:0048709	oligodendrocyte differentiation
GO:0051402	neuron apoptotic process
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
GO:1900119	positive regulation of execution phase of apoptosis