Version 5.4
Homo sapiens Protein: BTRC
Summary
InnateDB Protein IDBP-87106.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BTRC
Protein Name beta-transducin repeat containing
Synonyms BETA-TRCP; betaTrCP; bTrCP; bTrCP1; FBW1A; FBXW1; FBXW1A; FWD1;
Species Homo sapiens
Ensembl Protein ENSP00000359202
InnateDB Gene IDBG-87102 (BTRC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 252 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 252 [view]
Protein-Protein 249 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001810 F-box domain
IPR021977 D domain of beta-TrCP
PFAM PF00646
PF12937
PF13013
PF12125
PRINTS
PIRSF
SMART SM00256
SM01028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5T1W7
UniProt Splice Variant
Entrez Gene 8945
UniGene Hs.643802
RefSeq
HUGO HGNC:1144
OMIM 603482
CCDS
HPRD 04596
IMGT
EMBL AL133387 AL445463 AL627424
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca