Version 5.4
Homo sapiens Protein: CD40LG
Summary
InnateDB Protein IDBP-87657.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD40LG
Protein Name CD40 ligand
Synonyms CD154; CD40L; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP;
Species Homo sapiens
Ensembl Protein ENSP00000359662
InnateDB Gene IDBG-87653 (CD40LG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 13 [view]
Protein-DNA 8 [view]
Protein-RNA 2 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
Cellular Component
GO:0005615 extracellular space
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003263 Tumour necrosis factor ligand 5
IPR006052 Tumour necrosis factor domain
IPR008983 Tumour necrosis factor-like domain
PFAM PF00229
PRINTS PR01702
PIRSF PIRSF016527
SMART SM00207
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3LFI8
UniProt Splice Variant
Entrez Gene 959
UniGene Hs.592244
RefSeq
HUGO HGNC:11935
OMIM 300386
CCDS
HPRD 02311
IMGT
EMBL AF529195 AL135783 AY197739
GenPept AAP37943 AAQ09090

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca