Version 5.4
Homo sapiens Protein: VEGFA
Summary
InnateDB Protein IDBP-88732.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VEGFA
Protein Name vascular endothelial growth factor A
Synonyms MVCD1; VEGF; VPF;
Species Homo sapiens
Ensembl Protein ENSP00000230480
InnateDB Gene IDBG-88716 (VEGFA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 59 [view]
Protein-Protein 39 [view]
Protein-DNA 18 [view]
Protein-RNA 2 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0008201 heparin binding
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0051781 positive regulation of cell division
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000072 PDGF/VEGF domain
IPR027928 Vascular endothelial growth factor, heparin-binding domain
IPR029034 Cystine-knot cytokine
PFAM PF00341
PF14554
PRINTS
PIRSF
SMART SM00141
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2A2V4
UniProt Splice Variant
Entrez Gene 7422
UniGene Hs.732505
RefSeq NP_001273973
HUGO HGNC:12680
OMIM 192240
CCDS CCDS69125
HPRD 01889
IMGT
EMBL AL136131
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca