Homo sapiens Protein: ASAH1
Summary
InnateDB Protein IDBP-8959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASAH1
Protein Name N-acylsphingosine amidohydrolase (acid ceramidase) 1
Synonyms AC; ACDase; ASAH; PHP; PHP32; SMAPME;
Species Homo sapiens
Ensembl Protein ENSP00000326970
InnateDB Gene IDBG-8951 (ASAH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0017040 ceramidase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006665 sphingolipid metabolic process
GO:0006672 ceramide metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0008219 cell death
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005764 lysosome
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR016699 Acid ceramidase-like
IPR029055 Nucleophile aminohydrolases, N-terminal
IPR029132 Choloylglycine hydrolase/NAAA C-terminal
PFAM PF02275
PRINTS
PIRSF PIRSF017632
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13510
PhosphoSite PhosphoSite-Q13510
TrEMBL B1B5R9
UniProt Splice Variant
Entrez Gene 427
UniGene Hs.738809
RefSeq NP_001120977
HUGO HGNC:735
OMIM 613468
CCDS CCDS47813
HPRD 01969
IMGT
EMBL AB371370 AB371371 AB371380 AB371382 AB371383 AB371386 AC124242 AF220172 AF220173 AF220175 AY305384 BC016481 BC016828 U47674 U70063
GenPept AAC50907 AAC73009 AAF91230 AAH16481 AAH16828 AAQ75550 BAG12320 BAG12322 BAG12336 BAG12340 BAG12342 BAG12346