Version 5.4
Homo sapiens Protein: SSR4
Summary
InnateDB Protein IDBP-90040.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSR4
Protein Name signal sequence receptor, delta
Synonyms TRAPD;
Species Homo sapiens
Ensembl Protein ENSP00000317331
InnateDB Gene IDBG-90038 (SSR4)
Protein Structure
UniProt Annotation
Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Subcellular Localization Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006412 translation
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005784 Sec61 translocon complex
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008855 Translocon-associated
PFAM PF05404
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51571
PhosphoSite PhosphoSite-P51571
TrEMBL
UniProt Splice Variant
Entrez Gene 6748
UniGene Hs.409223
RefSeq NP_001191455
HUGO HGNC:11326
OMIM 300090
CCDS CCDS14731
HPRD 02101
IMGT
EMBL AK290493 BC003371 BC032351 BT007192 CH471172 U52111 X90583 Z68129 Z69043
GenPept AAH03371 AAP35856 BAF83182 CAA62211 CAA92215 CAA93157 EAW72811

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca