InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPL7A

Summary

InnateDB Protein

IDBP-91026.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL7A

Protein Name

ribosomal protein L7a

Synonyms

L7A; SURF3; TRUP;

Species

Homo sapiens

Ensembl Protein

ENSP00000361076

InnateDB Gene

IDBG-91022 (RPL7A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Note=Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene.

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 135 experimentally validated interaction(s) in this database.

Experimentally validated
Total	135 [view]
Protein-Protein	135 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0042254	ribosome biogenesis
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005829	cytosol
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0042788	polysomal ribosome
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001921 Ribosomal protein L7A/L8
IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45
IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family
IPR029064 50S ribosomal protein L30e-like

PFAM

PF01248

PRINTS

PR00882
PR00881

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P62424