InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SURF4

Summary

InnateDB Protein

IDBP-91145.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SURF4

Protein Name

surfeit 4

Synonyms

ERV29;

Species

Homo sapiens

Ensembl Protein

ENSP00000361057

InnateDB Gene

IDBG-91141 (SURF4)

Protein Structure

UniProt Annotation

Function

May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. {ECO:0000269PubMed:18287528}.

Subcellular Localization

Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.

Experimentally validated
Total	36 [view]
Protein-Protein	36 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007030	Golgi organization
GO:0010638	positive regulation of organelle organization

Cellular Component

GO:0000139	Golgi membrane
GO:0005789	endoplasmic reticulum membrane
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
GO:0016021	integral component of membrane
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane