InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IL9R

Summary

InnateDB Protein

IDBP-92625.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IL9R

Protein Name

interleukin 9 receptor

Synonyms

CD129; IL-9R;

Species

Homo sapiens

Ensembl Protein

ENSP00000244174

InnateDB Gene

IDBG-92623 (IL9R)

Protein Structure

UniProt Annotation

Function

This is a receptor for interleukin-9.

Subcellular Localization

Cell membrane; Single-pass type I membrane protein. Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004919	interleukin-9 receptor activity
GO:0005515	protein binding
GO:0019983	interleukin-9 binding

Biological Process

GO:0007165	signal transduction
GO:0008283	cell proliferation
GO:0030307	positive regulation of cell growth
GO:0038113	interleukin-9-mediated signaling pathway
GO:0045087	innate immune response

Cellular Component

GO:0005615	extracellular space
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003961 Fibronectin, type III

PFAM

PF00041
PF01108

PRINTS

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q01113

PhosphoSite

PhosphoSite-Q01113

TrEMBL

UniProt Splice Variant

Entrez Gene

3581

UniGene

Hs.720843

RefSeq

NP_002177

HUGO

HGNC:6030

OMIM

300007

CCDS

CCDS14771

HPRD

02052

IMGT

EMBL

AJ271736 AY071830 CH471247 L39064 M84747 S71404 S71420

GenPept

AAA58679 AAB30844 AAC29513 AAD14081 AAL55435 CAB96817 EAW55884